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Welcome to a brand new edition of SharpBrains e‑e-newsletter, featuring fascinating analysis discoverings on neuroplasticity, cognition, growing older, medication, Alzheimer’s, board video games, and extra, plus some mind teasers to get you in nice form for Halloween.
#1. Research: Playing board video games like Chess, Mahjong, Go, helps sluggish cognitive decline as we age (however with clear differences in neurobiology and improved perform)
So … let’s play all three!
#2. The Thoughtsful Physique argues in opposition to thoughtsmuch lessly settle foring age-related decline in cognition and well being as inevitable
“Perhaps Langer’s most provocative recommendation is reserved for doctors and others who deal with sickness, malestal or physical. When delivering information to sufferers, she writes, practitioners would do nicely to current diagnoses and prognoses in tentative methods, enableing for the possibility of being unsuitable and for extra optimistic outseems. By doing so, she says, practitioners may assist sufferers maintain freely the labels that make them see themselves in mounted methods and develop into, as a substitute, extra thoughtsful, lively participants in their very own well being care.”
#3. Harnessing Neuroplasticity, Medication AND Psychotherapy to deal with malestal well being circumstances
Nice summary: “… enhancing or modulating plasticity with a biological intervention like medication might not solely cut back symptoms however may additionally professionalvide a window of opportunity for behavioral interventions like psychotherapy to be extra effective. Be taughting-based interventions like cognitive-behavioral or expocertain therapy, if properly timed, may harness the improved neuroplasticity that biological interventions induce and enhance long-term outcomes.”
#4. Questions develop concerning the legitimateity and usefulness of direct-to-consumer blood assessments for Alzheimer’s Illness
“…scientists and clinicians worry that Quest hasn’t published any peer-reviewed studies documenting the check’s legitimateity. The corporate’s preliminary knowledge launched on the 2022 Alzheimer’s Association International Conference in San Diego suggests there’s a relatively excessive probability of false-positive outcomes … Specialists additionally question the usefulness of the check since a positive consequence (indicating abnormal levels of amyloid within the blood) doesn’t imply an individual will definitely develop Alzheimer’s disease. Amyloid within the mind accumulates sluggishly over the course of many years, typically startning in middle age, and turns into extra common as people age.”
#5. 4 reasons to question “new generation” monoclonal antiphysique Alzheimer’s medicine equivalent to aducanumab (Aduhelm), lecanemab (Leqembi), donanemab
1. Tiny benefits2. Facet effects3. Excessive prices4. Excessively selective trials
#6. Non-invasive Transcranial Electrical Stimulation (TES) reveals early promise to deal with ADHD symptoms in youngsters
“…promising consequence have been obtained in that children receiving lively deal withment confirmed significant reductions in parent-rated ADHD symptoms compared to those that acquired sham deal withment. … Furtherextra, these differences persisted throughout the three?week followup.”
#7. The NHS Confederation releases digital malestal well being whitepaper
“To do nothing is just not an choice. If we don’t make extra progress we miss a key opportunity to make enhancements to malestal well being services equivalent to improving entry; professionalviding early intervention and prevention at scale; implementing new methods of attaining people; and assisting to fulfill the demand supply hole; and on the identical time opening up entry in order that inequalities in entry to well beingcare and support for malestal well being are lowered.”
#8. Past the clinic: Can digital therapeutics (DTx) assist enhance malestal well being within the workdrive at scale?
“The digital therapeutics (DTx) indusattempt is at a crossroads after one of the prominent companies within the house, Pear Therapeutics, filed for financial institutionruptcy earlier this yr … there’s a transferment away from getting these products covered like a pharmacy benematch. As a substitute, many companies are looking to make offers with the make use ofer market.”
#9. Celebrate Halloween with 9 nice riddles about Life and Loss of life
Question: What is filled with hope, typically considered, however doesn’t exist?
#10. Mind Teaser: What shirt measurement you want now?
Have a fantastic month of November
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